Computational Biology and Chemogenomics Team Publications

Team Leader: Dr Bissan Al-Lazikani

Location: Haddow Laboratories, Sutton

Section: Cancer Research UK Cancer Therapeutics Unit

Agüero, F, Al-Lazikani, B, et. al. . “Genomic-scale Prioritisation of Drug Targets: TDRtargets.org”. Nat. Rev. Drug. Discov. (2008) In Press

Al-Lazikani, B, Hill, EE, Morea V. “Protein Structure Prediction”. Methods in Molecular Biology. Ed. Kieth, J. Humana Press, 2008 in press.

Al-Lazikani, B, Gaulton, A, Paolini, G, Lanfear, J, Overington, JP and Hopkins. AL “The Molecular Basis of Predicting Druggability.” Chemical Biology, Ed: Gunther Wess & Stuart Schreiber, Wiley, (2007)

Overington JP, Al-Lazikani, B and Hopkins AL. “How many drug targets are there?” Nat. Rev. Drug. Discov. (2006) 5:993-6.

Marks DJ, Harbord MW, MacAllister R, Rahman FZ, Young J, Al-Lazikani B, Lees W, Novelli M, Bloom S, Segal AW. “Defective acute inflammation
in Crohn's disease: a clinical investigation.” Lancet. (2006). 367:668-78.

Sheinerman FB, Al-Lazikani B, Honig B. “Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains.” J Mol Biol. (2003). 334:823-41.

Al-Lazikani B, Sheinerman FB, Honig B. “Combining multiple structure and sequence alignments to improve sequence detection and alignment: application to the SH2 domains of Janus kinases.” Proc Natl Acad Sci USA. (2001). 98:14796-801.